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KCNIP3 Antibody (Phospho-Ser63)

Product Specifications

CAS Number

9007-83-4

Gene Name

Potassium voltage-gated channel interacting protein 3

Gene Aliases

A-type potassium channel modulatory protein 3; calsenilin; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; DREAM; DRE-antagonist modulator; KCHIP3; Kv channel interacting protein 3, calsenilin; kv channel-interacting protein 3; potassium channel interacting protein 3.

Gene ID

30818

Swiss Prot

Q9Y2W7

Accession Number

NP_001030086.1

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human Calsenilin/KCNIP3 around the phosphorylation site of Ser63.

Target

Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Reconstitution

-20°C

Molecular Weight

29 kDa

Notes

Formerly GWB-ASB474

Fragment

IgG

Specificity

Calsenilin/KCNIP3 (Phospho-Ser63) antibody detects endogenous levels of Calsenilin/KCNIP3 only when phosphorylated at serine 63

NCBI Gene Symbol

KCNIP3

Host or Source

Rabbit

Protein Name

Calsenilin

Gene Name URL

KCNIP3

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