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KRT18 Antibody (Phospho-Ser52)

Product Specifications

CAS Number

9007-83-4

Gene Name

Keratin 18

Gene Aliases

Cell proliferation-inducing gene 46 protein; CK-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; keratin 18, type I; keratin, type I cytoskeletal 18; Keratin-18.

Gene ID

3875

Swiss Prot

P05783

Accession Number

NP_000215.1

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Keratin 18 around the phosphorylation site of Ser52.

Target

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

48 kDa

Notes

Formerly GWB-ASB398

Specificity

Cytokeratin 18 (Phospho-Ser52) antibody detects endogenous levels of Cytokeratin 18 only when phosphorylated at serine 52.

NCBI Gene Symbol

KRT18

Host or Source

Rabbit

Protein Name

Keratin, type I cytoskeletal 18

Gene Name URL

KRT18

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