GRIN1 Antibody (Phospho-Ser890)
Click here to learn more about Aviva's By-Request Conjugation Service.//here
Product Specifications
CAS Number
9007-83-4
Gene Name
Glutamate ionotropic receptor NMDA type subunit 1
Gene Aliases
GluN1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor ionotropic, NMDA 1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; MRD8; NDHMSD; NDHMSR; NMDA1; NMDAR1; NMD-R1; N-methyl-D-aspartate receptor channel, subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NR1; putative NMDtranscript (altAcc_e2) .
Gene ID
2902
Swiss Prot
Q05586
Accession Number
NP_000823.4
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human NMDAR1 around the phosphorylation site of Ser890.
Target
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280) . Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
105 kDa
Notes
Formerly GWB-ASB281
Specificity
GRIN1 (Phospho-Ser890) antibody detects endogenous levels of GRIN1 only when phosphorylated at serine 890.
NCBI Gene Symbol
GRIN1
Host or Source
Rabbit
Protein Name
Glutamate receptor ionotropic, NMDA 1
Gene Name URL
GRIN1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GYA81320-01 250 mg
(2-Chloro-4- (trifluoromethyl) phenyl) methanamine
Sign In for Pricing
View Details GYA81320-02 2.5 g
(2-Chloro-4- (trifluoromethyl) phenyl) methanamine
Sign In for Pricing
View Details