AKT1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
RAC-alpha serine/threonine-protein kinase
Gene Aliases
AKT, PKB, RAC, PRKBA, PKB-ALPHA, RAC-ALPHA
Gene ID
207
Swiss Prot
P31749
Accession Number
NP_001014431.1NP_001014432.1NP_005154.2XP_005267458.1
Reactivity
Human, Mouse, Rat, Chicken
Immunogen
Synthetic peptide corresponding to amino acids 461-477 of human PKBalpha/Akt1.
Target
PKBalphaalso knows as V-AKT murine thymoma vial oncogene homolog 1 (ATK1) . AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.
Clonality
Monoclonal
Clone
IML-26
Type
Monoclonal Antibody
Applications
WB
Purification
Purified by the goat anti-mouse IgG Affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Buffer
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Reconstitution
At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
Fragment
IgG1
NCBI Gene Symbol
AKT1
Host or Source
Mouse
Protein Name
RAC-alpha serine/threonine-protein kinase
Gene Name URL
AKT1
Nucleotide Accession Number
NM_001014431.1NM_001014432.1NM_005163.2XM_005267401.1
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