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CCND1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

G1/S-specific cyclin-D1

Gene Aliases

BCL1, PRAD1, U21B31, D11S287E

Gene ID

595

Swiss Prot

P24385

Accession Number

NP_444284.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human cyclin D1 protein.

Target

D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1 (CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

Clonality

Monoclonal

Clone

CY-D1

Type

Monoclonal Antibody

Applications

WB, IHC, IP, ICC

Purification

Purified by the goat anti-mouse IgG Affinity chromatography.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Buffer

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Reconstitution

At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.

Fragment

IgG2a

NCBI Gene Symbol

CCND1

Host or Source

Mouse

Protein Name

G1/S-specific cyclin-D1

Gene Name URL

CCND1

Nucleotide Accession Number

NM_053056.2

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