JUP Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Junction plakoglobin
Gene Aliases
PG, DP3, PDGB, PKGB, CTNNG, DPIII
Gene ID
3728
Swiss Prot
P14923
Accession Number
NP_002221.1NP_068831.1XP_006721936.1XP_006721937.1XP_006721938.1XP_006721941.1
Reactivity
Human, Rat, Chicken
Immunogen
Recombinant chicken plakoglobin.
Target
Junction Plakoglobin (JUP), also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.
Clonality
Monoclonal
Clone
CN-3
Type
Monoclonal Antibody
Applications
WB, IHC, ICC
Purification
Purified by the goat anti-mouse IgG Affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Buffer
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Reconstitution
At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
Fragment
IgG1
NCBI Gene Symbol
JUP
Host or Source
Mouse
Protein Name
Junction plakoglobin
Gene Name URL
JUP
Nucleotide Accession Number
NM_002230.2NM_021991.2XM_006721873.1XM_006721874.1XM_006721875.1XM_006721878.1
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