CD4 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

IMD79, OKT4D, CD4mut

Gene ID

920

Swiss Prot

P01730

Reactivity

Human

Immunogen

Human leucocytes

Target

Monoclonal Mouse Anti-Human CD4

Clonality

Monoclonal

Clone

B486 (EDU-2)

Type

Monoclonal Antibody

Applications

IHC, FC

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Concentrated

Reconstitution

Store at 2 - 8C for short term, freeze under -20C for long term storage.

Fragment

IgG2a

Specificity

This antibody reacts with a 55kD single chain transmembrane glycoprotien, CD4, expressed on T helper lymphocytes, dendritic cells, microglial cells, and cortical thymus cells. Characteristic of CD4 is its four extracellular immunoglobulin-like domains which help it bind to HLA class II molecules when CD4+ T cells interact with antigenpresenting cells or target cells. Another interesting aspect of the CD4 receptor is the fact that it also serves as the primary receptor for the HIV virus. This antibody was clustered at the 2nd International Leucocyte Typing Workshop.