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ZKSCAN3 Antibody - N-terminal region

Selected Variant

OAAB22289-200UL

Size: 200 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Zinc finger with KRAB and SCAN domains 3

Gene Aliases

ZF47, Zfp47, ZFP306, ZNF306, ZNF309, zfp-47, ZSCAN13, ZSCAN35, dJ874C20.1, dJ874C20.1.

Gene ID

80317

Swiss Prot

Q9BRR0

Accession Number

NP_001229823.1

Reactivity

Human, Mouse

Immunogen

This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.

Target

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Clonality

Polyclonal

Clone

RB53917

Type

Polyclonal Antibody

Applications

WB

Purification

Protein A column purification, followed by peptide affinity purification.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid.// PBS with 0.09% (W/V) sodium azide.

Reconstitution

Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61 kDa

Fragment

Rabbit Ig

NCBI Gene Symbol

ZKSCAN3

Host or Source

Rabbit

Gene Name URL

ZKSCAN3

Nucleotide Accession Number

NM_001242894.1

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