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TIMP2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TIMP metallopeptidase inhibitor 2

Gene Aliases

DDC8, CSC-21K

Gene ID

7077

Swiss Prot

P16035

Accession Number

NP_003246.1

Reactivity

Human, Mouse

Immunogen

This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.

Target

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Clonality

Monoclonal

Clone

1554CT494.262.47

Type

Monoclonal Antibody

Applications

WB

Purification

Protein G column purification, followed by dialysis against PBS

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

500 ug/mL

Homology

Human, Mouse

Format

Liquid

Reconstitution

Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

24 kDa

Fragment

IgG1, kappa

NCBI Gene Symbol

TIMP2

Host or Source

Mouse

Gene Name URL

TIMP2

Nucleotide Accession Number

NM_003255.4

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