ABCB11 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
ATP binding cassette subfamily B member 11
Gene Aliases
BSEP, PGY4, SPGP, ABC16, BRIC2, PFIC2, PFIC-2
Gene ID
8647
Swiss Prot
O95342
Accession Number
NP_003733.2
Reactivity
Human, Mouse
Immunogen
This ABCB11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1063-1097 amino acids of human ABCB11.
Target
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Clonality
Polyclonal
Clone
RB53271
Type
Polyclonal Antibody
Applications
WB
Purification
Protein A column purification, followed by peptide affinity purification
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
500 ug/mL
Homology
Human, Mouse
Format
Liquid
Reconstitution
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
146 kDa
Fragment
Rabbit Ig
NCBI Gene Symbol
ABCB11
Host or Source
Rabbit
Gene Name URL
ABCB11
Nucleotide Accession Number
NM_003742.2
Frequently Asked Questions
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