DGKA Antibody - C-terminal region
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable) . Can also phosphorylate 1-alkyl-2- acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol.
Product Specifications
CAS Number
9007-83-4
Gene Name
Diacylglycerol kinase alpha
Gene Aliases
Gene ID
1606
Swiss Prot
https://www.uniprot.org/uniprot/P23743
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001336.2,NP_958852.1,NP_958853.1,NP_963848.1
Reactivity
Human
Immunogen
Target
Diacylglycerol kinase alpha, diacylglycerol kinase alpha isoform a [Homo sapiens]
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Western blot
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Assay Protocol
Concentration
Varies by lot. See vial for concentration.
Homology
Human
Format
Liquid// PBS with 0.09% (W/V) sodium azide.
Reconstitution
Maintain refrigerated at 2-8° C for up to 2 weeks. For long term storage store at -20° C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
82630
Fragment
Ig
NCBI Gene Symbol
DGKA
Host or Source
Rabbit
Protein Name
NP_001336.2, NP_958852.1, NP_958853.1, NP_963848.1, P23743
Gene Name URL
DGKA
Frequently Asked Questions
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