URAT1&XO inhibitor 2
Selected Variant
HY-153972-01
Size: 5 mg
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia[1].
Product Specifications
CAS Number
1239488-96-0
UNSPSC
12352005
Target
URAT1; Xanthine Oxidase
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urat1-xo-inhibitor-2.html
Concentration
10mM
Purity
98.69
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
BrC(C=C1)=CC=C1C/C(C2=C(C=C(C=C2)O)O)=N\O
Molecular Formula
C14H12BrNO3
Molecular Weight
322.15
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MALT-1 (MT1/410), CF640R conjugate, 0.1mg/mL
Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (rBCL2/796), 0.2mg/mL
Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/2939R), CF740 conjugate, 0.1mg/mL
CD14 (Monocyte / Macrophage Marker) (LPSR/2397), CF594 conjugate, 0.1mg/mL
Milk Fat Globulin (EDM45), CF568 conjugate, 0.1mg/mL
