Kahweol
Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.
Product Specifications
CAS Number
6894-43-5
UNSPSC
12352005
Target
AMPK; Apoptosis
Type
Natural Products
Related Pathways
Apoptosis; Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/kahweol.html
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C5=C(OC=C5)C=C2)C[C@@]([C@](CO)(O)C4)([H])CC3
Molecular Formula
C20H26O3
Molecular Weight
314.42
References & Citations
[1]Seo HY, et al. Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway. Oncotarget. 2017 Aug 1;8 (50) :87086-87094.|[2]Baek JH, et al. Kahweol inhibits lipid accumulation and induces Glucose-uptake through activation of AMP-activated protein kinase (AMPK) . BMB Rep. 2017 Nov;50 (11) :566-571.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL306687V 500 µL Each
Ankyrin repeat domain containing protein 33 (ANKRD33) Human shRNA Lentiviral Particle (Locus ID 341405)
Sign In for Pricing
View Details 
37197126 3x 1.0µg DNA
POLR3G CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details 
MBS1229670-01 0.02 mg (E-Coli)
Recombinant Coffea arabica NAD (P)H-quinone oxidoreductase subunit J, chloroplastic
Sign In for Pricing
View Details