CCR3 Antibody - middle region
CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5) . It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
Product Specifications
CAS Number
9007-83-4
Gene Name
C-C motif chemokine receptor 3
Gene Aliases
Gene ID
1232
Swiss Prot
https://www.uniprot.org/uniprot/?query=P51677+OR+Q9BDS8
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_001828.1,NP_847898.1,NP_847899.1
Reactivity
Human, Primate
Immunogen
Target
C-C chemokine receptor type 3, C-C chemokine receptor type 3 isoform 1 [Homo sapiens], C-C chemokine receptor type 3 isoform 2 [Homo sapiens]
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Flow cytometry, Western blot
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Assay Protocol
Concentration
0.5 mg/ml
Homology
Human
Format
Liquid// PBS with 0.09% (W/V) sodium azide.
Reconstitution
Maintain refrigerated at 2-8° C for up to 2 weeks. For long term storage store at -20° C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
41044
Fragment
Rabbit Ig
NCBI Gene Symbol
CCR3
Host or Source
Rabbit
Protein Name
NP_001828.1, NP_847898.1, NP_847899.1, P51677, Q9BDS8
Gene Name URL
CCR3
Frequently Asked Questions
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