SORBS2 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
ARGBP2, PRO0618
Gene ID
8470
Swiss Prot
O94875
Accession Number
NP_001139142.1
Reactivity
Human
Immunogen
This ARGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.
Target
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, FC
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Varies by lot. See vial for concentration.
Homology
Human
Format
Liquid// PBS with 0.09% (W/V) sodium azide.
Reconstitution
Maintain refrigerated at 2-8° C for up to 2 weeks. For long term storage store at -20° C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
124 kDa
Fragment
Rabbit Ig
NCBI Gene Symbol
SORBS2
Host or Source
Rabbit
Protein Name
Sorbin and SH3 domain-containing protein 2
Gene Name URL
SORBS2
Frequently Asked Questions
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