ANGPTL3 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Aliases
ANL3, ANG-5, FHBL2, ANGPT5
Gene ID
27329
Swiss Prot
Q9Y5C1
Accession Number
NP_055310.1
Reactivity
Human, Mouse
Immunogen
This ANGPTL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-114 amino acids from the N-terminal region of human ANGPTL3.
Target
ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN) -like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Homology
Human; Mouse
Format
Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
53637 Da
Fragment
Ig
NCBI Gene Symbol
ANGPTL3
Host or Source
Rabbit
Protein Name
Angiopoietin-related protein 3
Gene Name URL
ANGPTL3
More Discoveries
Explore Other Products
Browse additional items from our catalog