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APBA1 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Amyloid beta (A4) precursor protein-binding, family A, member 1

Gene Aliases

X11, X11A, LIN10, MINT1, D9S411E, X11ALPHA

Gene ID

320

Swiss Prot

Q02410

Accession Number

EAW62487

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human APBA1

Target

APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.

Partner Proteins

STXBP1; CNTNAP4; NRXN1; CNTNAP3; KIF17; LIN7B; KCNJ12; CCS; CACNA1B; HTR2C; CASK; NOTCH1; STX1A; APP; PSEN1; LIN7A; PSEN2; LIN7C; DLG1; APBB1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

PPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTD

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

93kDa

Protein Length

837

NCBI Gene Symbol

APBA1

Host or Source

Rabbit

Protein Name

Amyloid beta A4 precursor protein-binding family A member 1

Gene Name URL

APBA1

Nucleotide Accession Number

NM_001163

Frequently Asked Questions

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