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RNASEL Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

Gene Aliases

RNS4, PRCA1

Gene ID

6041

Swiss Prot

Q05823

Accession Number

NP_066956

Reactivity

Human, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RNASEL

Target

This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

Partner Proteins

TCF12; UBC; ABCE1; AR; GSPT1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCDGA

Applications

WB

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 78%; Dog: 92%; Horse: 100%; Human: 100%; Pig: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

84kDa

Protein Length

741

NCBI Gene Symbol

RNASEL

Host or Source

Rabbit

Protein Name

2-5A-dependent ribonuclease

Gene Name URL

RNASEL

Nucleotide Accession Number

NM_021133

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