DOK2 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Docking protein 2, 56kDa
Gene Aliases
P56DOK, p56dok-2
Gene ID
9046
Swiss Prot
O60496
Accession Number
NP_003965
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2
Target
DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
Partner Proteins
UBC; RASA1; ABL1; POT1; EGFR; KIAA1279; INPP5D; NCK1; TEK; SRC; LYN; RET; LCK; IL4R; HCK; HSPA4L; ASF1B; DNAJB11; RAB10; SSSCA1; CFLAR; SPOP; SHC1; PSMD10; DOK1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QEPRGEAWRRQATRDRDPAGLQHVQPAGQDFSASGWQPGTEYDNVVLKKG
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 90%; Horse: 90%; Human: 100%; Mouse: 90%; Pig: 100%; Rat: 90%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
45kDa
Protein Length
412
NCBI Gene Symbol
DOK2
Host or Source
Rabbit
Protein Name
Docking protein 2
Gene Name URL
DOK2
Nucleotide Accession Number
NM_003974
Curated Selection
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