YWHAQ Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

Gene Aliases

1C5, HS1, 14-3-3

Gene ID

10971

Swiss Prot

P27348

Accession Number

NP_006817

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ

Target

YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Partner Proteins

UBC; TNFAIP3; TRIM42; RAF1; PIK3R2; PIK3C3; FUS; DTL; MAPT; ABL1; SGK1; SIK3; SUMO2; TUBGCP3; IRS4; HDAC5; HDAC4; STAU1; MDM2; TGM2; SMS; ALDH7A1; YWHAZ; YWHAH; GNAI3; G6PD; EIF5; EEF2; ECHS1; CAPNS1; CAPN1; LDHB; YWHAG; YWHAB; VCL; UBE2V1; TXNDC5; SMEK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSIC

Applications

IHC, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

28kDa

Protein Length

245

NCBI Gene Symbol

YWHAQ

Host or Source

Rabbit

Protein Name

14-3-3 protein theta

Gene Name URL

YWHAQ

Nucleotide Accession Number

NM_006826

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