RIPK2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Receptor-interacting serine-threonine kinase 2

Gene Aliases

CCK, RICK, RIP2, CARD3, GIG30, CARDIAK

Gene ID

8767

Swiss Prot

O43353

Accession Number

NP_003812

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RIPK2

Target

RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

RIPK2; XIAP; UBC; TRAF3; KDM3A; PRMT2; PELI3; NOD1; MAP3K7; CHUK; LRRK2; NOD2; TRAF4; TRAF6; MAP3K4; CASP12; NAT16; RNF31; RIPK1; MAVS; TRAF2; TAB2; TAB1; IKBKG; BIRC3; BIRC2; CARD16; CARD6; UBE2I; SMURF1; CFLAR; BCL10; TLR4; TLR2; TRAF5; CASP8; TRAF1; SM

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT

Applications

IF, WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 85%; Guinea Pig: 78%; Horse: 85%; Human: 85%; Mouse: 78%; Rabbit: 84%; Rat: 78%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

61kDa

Protein Length

540

NCBI Gene Symbol

RIPK2

Host or Source

Rabbit

Protein Name

Receptor-interacting serine/threonine-protein kinase 2

Gene Name URL

RIPK2

Nucleotide Accession Number

NM_003821

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