RIPK1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Receptor (TNFRSF) -interacting serine-threonine kinase 1

Gene Aliases

RIP, RIP1, AIEFL, IMD57, RIP-1

Gene ID

8737

Swiss Prot

Q13546

Accession Number

NP_003795

Reactivity

Human, Cow, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RIPK1

Target

FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.

Partner Proteins

RFFL; RIPK1; UBC; TRAF2; TRAF1; TNFRSF1A; TNF; OTUD1; YOD1; TRADD; IKBKG; FADD; CASP8; MAP3K7; BMH1; BIRC3; BIRC2; MAP3K8; OPTN; NUMBL; CFLAR; HSP90AA1; RIPK3; USP4; TNFAIP3; TNFSF10; LRRK2; TNFRSF10B; MAP3K3; HHV8GK18_gp80; DAB2IP; TNFRSF1B; IKBKB; CHUK

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQ

Applications

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 91%; Horse: 83%; Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

76kDa

Protein Length

671

NCBI Gene Symbol

RIPK1

Host or Source

Rabbit

Protein Name

Receptor-interacting serine/threonine-protein kinase 1

Gene Name URL

RIPK1

Nucleotide Accession Number

NM_003804

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