DIABLO antibody - C-terminal region (AVARP02023_T100)
Product Specifications
CAS Number
9007-83-4
Gene Name
Diablo, IAP-binding mitochondrial protein
Gene Aliases
SMAC, DFNA64
Gene ID
56616
Swiss Prot
Q502X2
Accession Number
NP_620308
Reactivity
Human, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human DIABLO
Target
DIABLO is an inhibitor of apoptosis protein (IAP) -binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
Partner Proteins
BIRC7; ARL6IP1; UBC; XIAP; BIRC2; BIRC6; BIRC3; MDM2; GABPA; AP1B1; SSRP1; ABCE1; GMPPB; LIMCH1; BMH1; AREL1; SLC25A47; MAML2; UBL4A; NR4A1; ARNT; MALT1; BIRC8; HTRA2; CDC40; DIABLO; ELAVL1; UBE2K; ZNF746; TOLLIP; UFM1; TRAF2; TRAF1; EEF1A1; Ngfrap1; BIRC
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
LVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRE
Applications
WB, IHC
Purification
Protein A purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1.0 mg/ml
Homology
Cow: 85%; Dog: 92%; Horse: 85%; Human: 100%; Pig: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
21kDa
Protein Length
186
NCBI Gene Symbol
DIABLO
Host or Source
Rabbit
Protein Name
Diablo homolog (Drosophila) EMBL AAH95468.1
Gene Name URL
DIABLO
Nucleotide Accession Number
NM_138930
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