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HIST3H3 Antibody - N-terminal region (AVARP01011_P050)

Selected Variant

AVARP01011_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone cluster 3, H3

Gene Aliases

H3t, H3.4, H3/g, H3FT, HIST3H3

Gene ID

8290

Swiss Prot

P84243

Accession Number

NP_003484

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HIST3H3

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Partner Proteins

RAD6; SETD7; WHSC1L1; PRDM2; WHSC1; KMT2A; PHF7; CBX5; TRIM28; ING2; UBC; K07C5.3; APLF; UHRF1; NEDD8; CUL4A; EZH2; ASF1B; ASF1A; MMS22L; IGSF8; TONSL; ICAM1; CD81; AURKA; MLLT1; TAF8; TAF3; TAF9B; PHF21A; ING4; PRAME; KAT6B; CBX6; PHF8; PHF2; ITGA4; TAF1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MARTKQTARKSTGGKAPRKQLATKVARKSAPATGGVKKPHRYRPGTVALR

Applications

WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

15kDa

Protein Length

136

NCBI Gene Symbol

HIST3H3

Host or Source

Rabbit

Protein Name

Histone H3.3

Gene Name URL

HIST3H3

Nucleotide Accession Number

NM_003493

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