ADRB2 antibody - middle region (AVARP00006_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Adrenergic, beta-2-, receptor, surface
Gene Aliases
BAR, B2AR, ADRBR, ADRB2R, BETA2AR
Gene ID
154
Swiss Prot
P07550
Accession Number
NP_000015
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ADRB2
Target
This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
ARRDC3; REL; TSHR; TSG101; STAT4; STAT3; SNCG; RGS10; RGS2; RAN; RAB27A; RAB3A; CNN1; CD81; CD68; CD9; CD4; CCKBR; CEACAM1; ARRB2; ARHGDIA; ARHGAP5; HDAC6; GPR56; VAPA; RGS9; RGS11; RGS20; RGS5; VEGFB; VDAC2; VDAC1; KCTD13; ARRDC1; RGS8; SLC52A2; WNK1; RA
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
TGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTN
Applications
WB
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
46kDa
Protein Length
413
NCBI Gene Symbol
ADRB2
Host or Source
Rabbit
Protein Name
Beta-2 adrenergic receptor
Gene Name URL
ADRB2
Nucleotide Accession Number
NM_000024
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
