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SQSTM1 Antibody Middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Sequestosome 1

Gene Aliases

P60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3

Gene ID

8878

Swiss Prot

Q13501-2

Accession Number

NP_001135770.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SQSTM1

Target

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPES

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

39 kDa

Protein Length

356

NCBI Gene Symbol

SQSTM1

Host or Source

Rabbit

Protein Name

Sequestosome-1

Gene Name URL

SQSTM1

Nucleotide Accession Number

NM_001142298.1

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