Anti-Dact2
Product Specifications
CAS Number
9007-83-4
Gene Name
Dishevelled-binding antagonist of beta-catenin 2
Gene Aliases
Dp, Frd, dap, Dpr2, Frd2, dapper2, A630024E20, 2900084M21Rik
Gene ID
240025
Swiss Prot
Q7TN08
Accession Number
NP_766414.3
Reactivity
Mouse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of mouse DACT2
Target
Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SRLRRQDAGLKTHLDQLDQQISELQLDVSRSSCEALDSDSRPSSGFYELS
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
82 kDa
Protein Length
757
NCBI Gene Symbol
DACT2
Host or Source
Rabbit
Protein Name
Dapper homolog 2
Gene Name URL
DACT2
Nucleotide Accession Number
NM_172826.3
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