What is the catalog number for PPP3CA Antibody - C-terminal region?

The catalog number for PPP3CA Antibody - C-terminal region is ARP90315_P050-25UL.

What sizes are available for PPP3CA Antibody - C-terminal region?

PPP3CA Antibody - C-terminal region is available in the following size(s): 25 µL.

Is PPP3CA Antibody - C-terminal region in stock?

PPP3CA Antibody - C-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

PPP3CA Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 3, catalytic subunit, alpha isoform

Gene Aliases

C, CN, CnA, Caln, Calna, 2900074D19Rik

Gene ID

19055

Swiss Prot

P63328

Accession Number

NP_001280551.1

Reactivity

Mouse

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of mouse PPP3CA

Target

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca2+-mediated signals. Many of the substrates contain a PxIxIT motif and/or a LxVP motif (By similarity) . In response to increased Ca2+Â levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (By similarity) . In response to increased Ca2+Â levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (By similarity) . Dephosphorylates heat shock protein HSPB1 (By similarity) . Dephosphorylates and activates transcription factor NFATC1 (By similarity) . Dephosphorylates and inactivates transcription factor ELK1 (By similarity) . Dephosphorylates DARPP32 (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

EEAKGLDRINERMPPRRDAMPSDANLNSINKALASETNGTDSNGSNSSNI

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol