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PMAIP1 Antibody - middle region (ARP89773_P050)

Selected Variant

ARP89773_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Phorbol-12-myristate-13-acetate-induced protein 1

Gene Aliases

N, Noxa

Gene ID

58801

Swiss Prot

Q9JM54

Accession Number

NP_067426.1

Reactivity

Mouse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Mouse PMAIP1

Target

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity) . Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TWSAPDITVVLAQMPGKSQKSRMRSPSPTRVPADLKDECAQLRRIGDKVN

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

11 kDa

Protein Length

103

NCBI Gene Symbol

PMAIP1

Host or Source

Rabbit

Protein Name

Phorbol-12-myristate-13-acetate-induced protein 1

Gene Name URL

PMAIP1

Nucleotide Accession Number

NM_021451.2

Price

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