Sobuzoxane
Sobuzoxane (MST-16) is an orally active topoisomerase II inhibitor. Sobuzoxane causes irreversible inhibition of cell division. Sobuzoxane can be used in the study of non-Hodgkin's lymphoma that is resistant to conventional chemotherapy or has recurred[1].
Product Specifications
CAS Number
98631-95-9
Product Name Alternative
MST 16
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sobuzoxane.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)COC(OCN1C(CN(CCN(C2)CC(N(COC(OCC(C)C)=O)C2=O)=O)CC1=O)=O)=O
Molecular Formula
C22H34N4O10
Molecular Weight
514.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Okamoto T, et al. Long-term administration of oral low-dose topoisomerase II inhibitors, MST-16 and VP-16, for refractory or relapsed non-Hodgkin’s lymphoma[J]. Acta Haematologica, 2001, 104 (2-3) : 128-130.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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