MCRS1 Antibody (ARP88700_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Microspherule protein 1
Gene Aliases
P78, MCRS2, MSP58, INO80Q, ICP22BP
Gene ID
10445
Swiss Prot
Q96EZ8
Accession Number
NP_001012300.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MCRS1
Target
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homopolymer poly (G) and poly (U) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
SEDEESLAGQKRASSQALGTIPKRRSSSRFIKRKKFDDELVESSLAKSST
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
50 kDa
Protein Length
462
NCBI Gene Symbol
MCRS1
Host or Source
Rabbit
Protein Name
Microspherule protein 1
Gene Name URL
MCRS1
Nucleotide Accession Number
NM_001012300.1
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