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MPRIP Antibody - N-terminal region (ARP86553_P050)

Selected Variant

ARP86553_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Myosin phosphatase Rho interacting protein

Gene Aliases

MRIP, RIP3, M-RIP, RHOIP3, p116Rip

Gene ID

23164

Swiss Prot

Q6WCQ1-3

Accession Number

NP_055949.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MPRIP

Target

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RTNKQNQKKKRKVEPPTPQEPGPAKVAVTSSSSSSSSSSSIPSAEKVPTT

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

110 kDa

Protein Length

1000

NCBI Gene Symbol

MPRIP

Host or Source

Rabbit

Protein Name

Myosin phosphatase Rho-interacting protein

Gene Name URL

MPRIP

Nucleotide Accession Number

NM_015134.3

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