NRBF2 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Nuclear receptor binding factor 2
Gene Aliases
COPR, COPR1, COPR2, NRBF-2
Gene ID
29982
Swiss Prot
Q96F24
Accession Number
NP_001269334.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NRBF2
Target
May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro) . Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1) . However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
EFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPP
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
31 kDa
Protein Length
287
NCBI Gene Symbol
NRBF2
Host or Source
Rabbit
Protein Name
Nuclear receptor-binding factor 2
Gene Name URL
NRBF2
Nucleotide Accession Number
NM_001282405.1
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