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HSPA14 Antibody - C-terminal region

Product Specifications

Gene Name

Heat shock protein family A (Hsp70) member 14

Gene Aliases

HSP70-4, HSP70L1

Gene ID

51182

Swiss Prot

Q0VDF9

Accession Number

NP_057383.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human HSPA14

Target

Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity. Acts as a potent immunoadjuvant, capable to interact with antigen-presenting cells and generating efficient CD8+ T-cell responses. May be used as adjuvant to enhance effect of vaccine G1F/M2, a candidate vaccine against respiratory syncytial virus (RSV), a major respiratory pathogen in newborns. May also be used as adjuvant to prepare antigenic fusion protein for the therapeutics of cancers.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

SSVCLELYESDGKNSAKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDG

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

55 kDa

Protein Length

509

NCBI Gene Symbol

HSPA14

Host or Source

Rabbit

Protein Name

Heat shock 70 kDa protein 14

Gene Name URL

HSPA14

CAS Number

9007-83-4

Nucleotide Accession Number

NM_016299.3

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