Anti-Mouse FGL-1 Antibody (177R4)
Selected Variant
HY-P990243
Size: 1 Each
Anti-Mouse FGL-1 Antibody (177R4) is an anti-mouse FGL-1 IgG2a monoclonal antibody. Anti-Mouse FGL-1 Antibody (177R4) can increase CD8+ T cell infiltration. Anti-Mouse FGL-1 Antibody (177R4) enhances the anti-tumor immune effect by blocking FGL1. Anti-Mouse FGL-1 Antibody (177R4) can be used for research on cancer such as lung cancer and breast cancer[1][2].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
LAG-3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-mouse-fgl-1-antibody-177r4.html
Solubility
10 mM in DMSO
Smiles
[Anti-MouseFGL-1Antibody(177R4)]
Molecular Weight
(150 kDa)
References & Citations
[1]Jiang J, et al. Yap methylation-induced FGL1 expression suppresses anti-tumor immunity and promotes tumor progression in KRAS-driven lung adenocarcinoma. Cancer Commun (Lond) . 2024 Nov;44 (11) :1350-1373.|[2]Yangyang Xia, et al. ALKBH5 enhances efficiency of anti-PD-1/PD-L1 therapy by reducing Lnc-XIST/miRNA- 124-3p mediated FGL1 expression in bladder cancer , 11 October 2022, PREPRINT (Version 1) .
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Price
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