APPL1 Antibody - C-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Gene Aliases
APPL, MODY14, DIP13alpha
Gene ID
26060
Swiss Prot
Q9UKG1
Accession Number
NP_036228.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human APPL1
Target
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
QIEKDLEEQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRES
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
80 kDa
Protein Length
709
NCBI Gene Symbol
APPL1
Host or Source
Rabbit
Protein Name
DCC-interacting protein 13-alpha
Gene Name URL
APPL1
Nucleotide Accession Number
NM_012096.2
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