AEN Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Apoptosis enhancing nuclease
Gene Aliases
ISG20L1, pp12744
Gene ID
64782
Swiss Prot
Q8WTP8
Accession Number
NP_073604.3
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AEN
Target
Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
REAPESAQCLCPSLTIPNAKDVLRKRHKRRSRQHQRFMARKALLQEQGLL
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
35 kDa
Protein Length
325
NCBI Gene Symbol
AEN
Host or Source
Rabbit
Protein Name
Apoptosis-enhancing nuclease
Gene Name URL
AEN
Nucleotide Accession Number
NM_022767.3
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