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HNMT Antibody - middle region (ARP81432_P050)

Selected Variant

ARP81432_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Histamine N-methyltransferase

Gene Aliases

HMT, MRT51, HNMT-S1, HNMT-S2

Gene ID

3176

Swiss Prot

P50135

Accession Number

NP_001019245.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HNMT

Target

In mammals, histamine is metabolized by two major pathways: N (tau) -methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N (tau) -methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

STMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEF

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

32 kDa

Protein Length

292

NCBI Gene Symbol

HNMT

Host or Source

Rabbit

Protein Name

Histamine N-methyltransferase

Gene Name URL

HNMT

Nucleotide Accession Number

NM_001024074.2

Price

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