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BUB1B Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

BUB1 mitotic checkpoint serine/threonine kinase B

Gene Aliases

MVA1, SSK1, BUBR1, Bub1A, MAD3L, hBUBR1, BUB1beta

Gene ID

701

Swiss Prot

O60566-2

Accession Number

NP_001202.4

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BUB1B

Target

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

AFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQ

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

102 kDa

Protein Length

933

NCBI Gene Symbol

BUB1B

Host or Source

Rabbit

Protein Name

Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Gene Name URL

BUB1B

Nucleotide Accession Number

NM_001211.5

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