What is the catalog number for GLDC Antibody - N-terminal region (ARP80472_P050)?

The catalog number for GLDC Antibody - N-terminal region (ARP80472_P050) is ARP80472_P050.

What sizes are available for GLDC Antibody - N-terminal region (ARP80472_P050)?

GLDC Antibody - N-terminal region (ARP80472_P050) is available in the following size(s): 100 µL.

Is GLDC Antibody - N-terminal region (ARP80472_P050) in stock?

GLDC Antibody - N-terminal region (ARP80472_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

GLDC Antibody - N-terminal region (ARP80472_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Glycine dehydrogenase (decarboxylating)

Gene Aliases

GCE, GCSP, HYGN1

Gene ID

2731

Swiss Prot

P23378

Accession Number

NP_000161.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GLDC

Target

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase) . The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

LAGGSGPCWAPRSRDSSSGGGDSAAAGASRLLERLLPRHDDFARRHIGPG

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

112 kDa

Protein Length

1020

NCBI Gene Symbol

GLDC

Host or Source

Rabbit

Protein Name

Glycine dehydrogenase (decarboxylating), mitochondrial

Gene Name URL

GLDC

Nucleotide Accession Number

NM_000170.2

Frequently Asked Questions

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