DIS3L Antibody - middle region (ARP80283_P050)
Selected Variant
ARP80283_P050
Size: 100 µL
Product Specifications
CAS Number
9007-83-4
Gene Name
DIS3 like exosome 3'-5' exoribonuclease
Gene Aliases
DIS3L1
Gene ID
115752
Swiss Prot
Q8TF46-4
Accession Number
NP_001137160.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DIS3L
Target
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
AAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGI
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
106 kDa
Protein Length
971
NCBI Gene Symbol
DIS3L
Host or Source
Rabbit
Protein Name
DIS3-like exonuclease 1
Gene Name URL
DIS3L
Nucleotide Accession Number
NM_001143688.1
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