What is the catalog number for FLT3 Antibody - N-terminal region?

The catalog number for FLT3 Antibody - N-terminal region is ARP79517_P050-25UL.

What sizes are available for FLT3 Antibody - N-terminal region?

FLT3 Antibody - N-terminal region is available in the following size(s): 25 µL.

Is FLT3 Antibody - N-terminal region in stock?

FLT3 Antibody - N-terminal region is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

FLT3 Antibody - N-terminal region

Selected Variant

ARP79517_P050-25UL

Size: 25 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Fms related tyrosine kinase 3

Gene Aliases

FLK2, STK1, CD135, FLK-2

Gene ID

2322

Swiss Prot

P36888-2

Accession Number

NP_004110.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FLT3

Target

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPEDLGCALRPQS

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

108 kDa

Protein Length

952

NCBI Gene Symbol

FLT3

Host or Source

Rabbit

Protein Name

Receptor-type tyrosine-protein kinase FLT3

Gene Name URL

FLT3

Nucleotide Accession Number

NM_004119.2

Price

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