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DROSHA Antibody - middle region (ARP77320_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

Drosha, ribonuclease type III

Gene Aliases

RN3, ETOHI2, RNASEN, RANSE3L, RNASE3L, HSA242976

Gene ID

29102

Swiss Prot

Q9NRR4

Accession Number

NP_001093882.1

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DROSHA

Target

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]) . The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]) .[supplied by OMIM, Mar 2008]

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

RGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERER

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

159 kDa

Protein Length

215

NCBI Gene Symbol

DROSHA

Host or Source

Rabbit

Protein Name

Ribonuclease 3

Gene Name URL

DROSHA

Nucleotide Accession Number

NM_001100412.1

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