DROSHA Antibody - middle region (ARP77320_P050)
Product Specifications
CAS Number
9007-83-4
Gene Name
Drosha, ribonuclease type III
Gene Aliases
RN3, ETOHI2, RNASEN, RANSE3L, RNASE3L, HSA242976
Gene ID
29102
Swiss Prot
Q9NRR4
Accession Number
NP_001093882.1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human DROSHA
Target
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]) . The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]) .[supplied by OMIM, Mar 2008]
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERER
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
159 kDa
Protein Length
215
NCBI Gene Symbol
DROSHA
Host or Source
Rabbit
Protein Name
Ribonuclease 3
Gene Name URL
DROSHA
Nucleotide Accession Number
NM_001100412.1
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