What is the catalog number for PDE6A Antibody - middle region (ARP76442_P050)?

The catalog number for PDE6A Antibody - middle region (ARP76442_P050) is ARP76442_P050.

What sizes are available for PDE6A Antibody - middle region (ARP76442_P050)?

PDE6A Antibody - middle region (ARP76442_P050) is available in the following size(s): 100 µL.

Is PDE6A Antibody - middle region (ARP76442_P050) in stock?

PDE6A Antibody - middle region (ARP76442_P050) is currently made to order / not held in immediate stock. Contact us for lead time.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

PDE6A Antibody - middle region (ARP76442_P050)

Selected Variant

ARP76442_P050

Size: 100 µL

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphodiesterase 6A, cGMP-specific, rod, alpha

Gene Aliases

PDEA, RP43, CGPR-A

Gene ID

5145

Swiss Prot

P16499

Accession Number

NP_000431.2

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PDE6A

Target

This gene encodes the cyclic-GMP (cGMP) -specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

YTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVPPYSGPRTPDGREI

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

100 kDa

Protein Length

167

NCBI Gene Symbol

PDE6A

Host or Source

Rabbit

Protein Name

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

Gene Name URL

PDE6A

Nucleotide Accession Number

NM_000440.2

Price

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