GCP4 Antibody - C-terminal region (ARP75532_P050)
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Product Specifications
CAS Number
9007-83-4
Gene Name
Tubulin gamma complex associated protein 4
Gene Aliases
76P, GCP4, GCP-4, Grip76, MCCRP3
Gene ID
27229
Swiss Prot
Q9UGJ1
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCP4
Target
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.
Partner Proteins
GLYCTK; RNF146; FBXW11; RPS8; RPS3A; RPS3; RPLP2; RPL38; RPL27; RPS26P50; TUBB; NEDD1; TUBA1C; UQCC2; MZT2B; MRPS24; MRPS14; MRPS23; MRPS7; MRPS18B; TUBGCP2; IGF2BP1; TUBGCP3; TUBB4B; RPL14; DGCR6; TUBA1A; UBB; TUBG1; TUBB2A; RPS27; RPS19; RPS16; HSPA9; H
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KGFSRQSSLLFKILSSVRNHQINSDLAQLLLRLDYNKYYTQAGGTLGSFG
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
73kDa
Protein Length
667
NCBI Gene Symbol
TUBGCP4
Host or Source
Rabbit
Protein Name
Gamma-tubulin complex component 4
Gene Name URL
TUBGCP4
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