WAPL Antibody - middle region
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Product Specifications
CAS Number
9007-83-4
Gene Aliases
FOE, WAPAL, KIAA0261
Gene ID
23063
Swiss Prot
Q7Z5K2
Accession Number
NP_055860
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human WAPL
Target
WAPL is a regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. It is involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. It couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Partner Proteins
UBC; RPA3; RPA2; RPA1; XRN1; PDS5A; SMC3; VCP; VPS16; WRAP53; USP15; USP10; NSMCE2; ELAVL1; SUMO2; RAD21; ARAP1; Stag2; WAPAL; PDS5B; STAG1; SMC1A; SRRM1
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDD
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
130kDa
Protein Length
1190
NCBI Gene Symbol
WAPL
Host or Source
Rabbit
Gene Name URL
WAPL
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