CD2B2 Antibody - C-terminal region (ARP75354_P050)

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Product Specifications

CAS Number

9007-83-4

Gene Name

CD2 cytoplasmic tail binding protein 2

Gene Aliases

LIN1, Snu40, FWP010, U5-52K, PPP1R59

Gene ID

10421

Swiss Prot

O95400

Accession Number

NP_006101

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD2B2

Target

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Partner Proteins

SNRPB; PPP1CC; USP19; UBC; PPP1CA; CSNK2A1; SMU1; PRPF6; PAXIP1; PRPF8; SNRNP40; UBE2V2; SNRPF; SH3BGRL; SGTA; S100A9; S100A6; RAB5B; PSMD9; PLP2; GINS4; TBL1XR1; GINS3; EP400; UBQLN4; POMP; COTL1; MGA; SNRNP200; AHCYL1; AKNA; WBP11; PSMF1; CUL3; CD2; SF3

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

DAELYGPFTSAQMQTWVSEGYFPDGVYCRKLDPPGGQFYNSKRIDFDLYT

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol