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PPP6R2 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 6 regulatory subunit 2

Gene Aliases

PP6R2, SAPS2, SAP190, KIAA0685

Gene ID

9701

Swiss Prot

O75170

Accession Number

XP_006724497

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PP6R2

Target

The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment.

Partner Proteins

AURKA; ANKRD52; WDR92; MOB1B; ANKRD44; SH3GLB2; PPP6R3; MOB1A; CACYBP; DPCD; NUDC; PFDN6; AIP; TTC1; PPP6C; ANKRD28; PPP6R1; ILVBL; RUVBL2; PLK1; PFDN5; PFDN2; ACSL3; ALDH3A2; APP; ATXN1; PRKDC; USP49; SIT4; TBK1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FVDQFGFNDEEFADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCS

Applications

WB

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

106kDa

Protein Length

966

NCBI Gene Symbol

PPP6R2

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 6 regulatory subunit 2

Gene Name URL

PPP6R2

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