USP14 Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Ubiquitin specific peptidase 14

Gene Aliases

TGT

Gene ID

9097

Swiss Prot

P54578

Accession Number

NP_005142

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBP14

Target

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

UBC; UBP6; PSMD2; HTT; ERN1; CLB1; SHFM1; RPL23; RPL30; RAP1GDS1; GSS; ECHS1; CNDP2; RNF11; PFAS; HNRNPK; VPS37B; UNC45A; WDR12; XPO7; PSMD14; XPO1; UBE3A; UBE2N; PSMD13; PSMD12; PSMD7; PSMC6; PSMC4; PSMC3; USP28; USP21; USP15; PSMD4; PSMA2; RAD23A; PSMC5

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

FKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAV

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol