PKM Antibody - C-terminal region

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Product Specifications

CAS Number

9007-83-4

Gene Name

Pyruvate kinase M1/2

Gene Aliases

PK3, TCB, p58, OIP3, PKM2, CTHBP, THBP1, HEL-S-30

Gene ID

5315

Swiss Prot

P14618

Accession Number

XP_005254502

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human KPYM

Target

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.

Partner Proteins

LNX1; NXT2; HUWE1; ISG15; UBC; POLE2; FUS; SUMO2; SUMO3; STAU1; MDM2; SUZ12; EZH2; IPO11; TWF2; PDLIM5; NPLOC4; PLIN3; UBA2; EIF4A3; ANP32A; SRP14; RAD23B; PPP1CA; PIN1; CTPS1; CBS; CAPZA2; ACAT2; NLK; FBXO6; YWHAQ; RAF1; IGSF8; HDAC6; MAPK7; NPM1; CDK2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLE

Applications

Purification

Affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol